Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 1999 Jul 12;146(1):13–28. doi: 10.1083/jcb.146.1.13

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 1999 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Relationship of Bub1 to other kinetochore components. In all panels, DNA is in blue. Neuroblasts were treated with colchicine in all panels except D. (A) Bub1 (red) in a zw10^S1/Y mutant neuroblast. Note the Bub1 staining at the kinetochores of separated sister chromatids. (B) ZW10 (red) stains the kinetochores in bub1 mutant neuroblasts. (C) In neuroblasts homozygous for the mutation polo¹, Bub1 associates with the kinetochores. (D) In bub1 mutant neuroblasts (here shown at anaphase), Polo protein is bound to the kinetochores of the separating chromosomes, as in wild-type. (E) Null mutations in rough deal (rod) do not prevent the association of Bub1 with kinetochores. (F) Bub1 also binds to kinetochores in the neuroblasts of animals homozygous for the mutation fizzy⁶. Bar, 5 μm.