Figure 7.

Lack of anterior horn cell changes in old NF-deficient mice. In A–C, phase contrast images are shown of toluidine blue–stained sections of lumbar spinal cord from 2-yr-old wild-type (A), NF-M– (B), or NF-M/H– (C) null mutant animals. In D–H immunoperoxidase-stained sections of lumbar spinal cord are illustrated from wild-type (D and G), NF-M– (E and H), or NF-M/H– (F) null mutant animals stained with an NF-L antibody (D–F) or SMI-32 (G and H). No significant differences between NF-M or NF-M/H mutants and wild-type were noted. Bar, 20 μm.