Table 3.
Multiple Regression Predictors of Inflammation In Response to Chemotherapy
| Inflammatory Marker | Individual predictor variables (β coefficients; p values) | Model R2; adjusted R2; p value |
|---|---|---|
| CRP | Pre-chemotherapy CRP (.526; 0.023) | .177; .147; .023 |
| TNF-α | Pre-chemotherapy TNF-α (.322; 0.007) | .257; .227; 0.007 |
| IL1-RA | Pre-chemotherapy IL1-RA (−.159; .379); ER+ status (−.330; .069) | .133; .069; 0.146 |
| VEGF | Pre-chemotherapy VEGF (.374; .009); tumor size (−.104; 0.028) | .342; .009; .004 |
| sICAM-1 | Pre-chemotherapy sICAM-1 (.620; 0.001) | .396; .369; 0.001 |
| IL-6 | Pre-chemotherapy IL-6 (.588; 0.009); tumor size (.078; .041) | .311; .262;0.005 |
| sP-selectin | Pre-chemotherapy sP-selectin (.096; 0.52); tumor size (−.052; .008); chemotherapy (.069; 0.014) | .436; .349; 0.0048 |
| vWf | Pre-chemotherapy vWf (.706; 0.001) | .335; .332; 0.001 |