Table 1.
Patient characteristics (no. 1–3: primary bone tumors; 4–15: solitary metastases), tumor type, location, primary tumor site, type according to the surgical classification of spinal tumors of Tomita [32], revised Tokuhashi prognostic score [30], disease-free survival before the appearance of metastases, preoperatively diagnosed neurological symptoms, previous therapy, surgical margins and current oncological status
Number | Sex/age | Histology | Site/resected segment | Primary tumor site (adjuvant therapy) | Classification (Tomita) | Tokuhashi prognostic score (metastatic tumors) | Diseases-free survival before metastasis (months) | Preoperative neurological symptoms | Multimodal therapy chemo: C radiation: R | Surgical margins | Cumulative disease specific survival (months) | Cumulative metastases free survival (months) | Oncolog status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | M/55 | Malignant fibrous histiocytoma | Th 2/3 | – | 6 | – | – | Paraparesis emergency laminectomy | C (neoadjuvant) | Marginal | 52 | 52 | NED |
2 | F/33 | Pleomorphous sarcoma | Th 9/10/11 | – | 6 | – | – | – | C (neoadjuvant) | Wide | 51 | 51 | NED |
3 | M/12 | Osteosarcoma | Th 1 | – | 5 | – | – | Paraparesis emergency laminectomy | C + R (neoadjuvant) | Marginal | 40 | 40 | NED |
4 | F/54 | Leiomyosarcoma | L 1 | Left thigh (no) | 2 | 12 | 98 | Radicular (L1) | – | Wide | 57 | 57 | NED |
5 | M/56 | Renal cell Ca | Th 8 | Left kidney (no) | 2 | 13 | 5 | – | R | Wide | 16 | 12 | DOD |
6 | F/59 | Leiomyosarcoma | L 2/3 | Retroperitoneum (no) | 6 | 11 | 66 | – | C + R | Wide | 4 | 2 | DOD |
7 | M/5 | Teratoma | L 2 | Left groin (radiation) | 4 | 12 | 23 | – | C | Marginal | 75 | 75 | NED |
8 | M/22 | Seminoma | Th 9 | Right testes (chemotx) | 4 | 11 | 12 | – | C + R (neoadjuvant) | Marginal | 44 | 44 | NED |
9 | F/58 | Mamma-Ca | Th 11 | Right mamma (tamoxifen) | 2 | 15 | 56 | – | – | Wide | 44 | 44 | NED |
10 | M/44 | Renal cell Ca | L 4 | Right kidney (no) | 2 | 11 | 12 | – | C | Wide | 25 | 3 | AWD |
11 | F/52 | Mamma-Ca | L 5 | Right mamma (tamoxifen) | 2 | 14 | 46 | – | C | Wide | 41 | 4 | AWD |
12 | F/72 | Malignant schwannoma | L2 | Left forearm (no) | 5 | 12 | 44 | – | R | Marginal | 19 | 19 | NED |
13 | F/67 | Mamma-Ca | Th10 | Left mamma (no) | 2 | 15 | 81 | – | – | Wide | 18 | 18 | NED |
14 | M/62 | Renal cell Ca | Th6 | Right kidney (no) | 2 | 13 | 180 | – | – | Wide | 4 | 4 | NED |
15 | M/49 | Renal cell Ca | Th9 | Left kidney (no) | 2 | 13 | 151 | – | – | Wide | 2 | 2 | NED |
Patient no. 2 received mulitvisceral resection (Th 9/10/11, lower lung lobe, diaphragm, parts of the chest wall en bloc) DOD dead of disease, AWD alive with disease, NED no evidence of disease