Table 2.

Multivariate analysis of overall survival in 86 T-PLL patients based on Cox proportional hazards model integrating molecular and clinical features

Prognostic factor	Risk of disease-related death
	Relative risk	Standard error	P
Model including tumor features and age
Age over 65 y	1.9	0.26	.015
High TCL1	1.7	0.28	.049
pAKT-S473+	2.9	0.45	.03
sTCR+	2.2	0.37	.02
Model with inclusion of clinical parameters
Age over 65 y	2.4	0.27	.001
WBC count over 40 ×109/L*	2.2	0.28	.006
LDT, 3-tier*	2.2	0.22	<.001
sTCR+	2.6	0.37	.01

^*Both TCL1 and pAKT levels showed a strong positive correlation with each of these clinical parameters and were therefore not retained in this regression analysis.