Table 2.
Efficiency of single-colony infections using primary HIV-1 isolates.
Colony type | 30165 (B) | 92US657 (B) | 92US712 (B) | 92US714 (B) | 92US727 (B) | BW1841 (C) | BW2031 (C) | BW2036 (C) | BW2041 (C) | BW5042 (C) |
---|---|---|---|---|---|---|---|---|---|---|
BFU-E | 0/27 | 0/19 | 0/22 | 0/26 | 0/27 | 0/41 | 0/45 | 2/54 | 0/49 | 1/22 |
CFU-GM | 0/37 | 0/23 | 0/27 | 2/34 | 0/35 | 7/52* | 2/48 | 7/61* | 2/76 | 8/31** |
CFU-GEMM | 0/1 | 0/2 | N/A | 0/3 | 0/4 | 0/2 | 0/5 | 0/9 | 0/7 | 2/22 |
Total (%) | 0/65 (0.0) | 0/44 (0.0) | 0/49 (0.0) | 2/63 (3.2) | 0/66 (0.0) | 7/95* (7.4) | 2/98 (2.0) | 9/124* (7.3) | 2/132 (1.5) | 11/75** (14.7) |
Data are numbers of infected colonies over numbers of single colonies tested. Primary isolate colonies were tested using hydrolysis probe technique.16 Viral subtype is shown in parentheses in column heads. All categories were compared with HXB2RU3CI for statistical significance by Fisher exact test.
P < .05,
P < .001.