Figure 2.

Immunohistochemical detection of MICA/B in epithelial tumors by staining with mAb 6D4. (A) Normal breast tissue. (B) Breast carcinoma. (C) Lung carcinoma. (D) Normal kidney. (E) Renal cell carcinoma. (F) Ovary carcinoma. Sections in A and B and C–F were from paraffin-embedded and frozen specimens, respectively. Nuclei were counterstained with hematoxylin (see Materials and Methods). These images were representative of stainings of numerous control tissue and tumor specimens. See text for further explanation.