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. 1999 Jun 8;96(12):6896–6901. doi: 10.1073/pnas.96.12.6896

Table 2.

Ratios of red vs. green T cells in different organs of (PL × SJL)F1 mice 18-24 h after adoptive transfer

Red:green cells coated with mAbs* Cell mix at time of injection Brain Spleen Liver
Antiintegrin α4 mAb vs. control mAb
 R1–2 (α4):53.7.3 (control), n = 2 1.0 0.78 0.89 0.97
 R1–2 (α4):GK 1.5(control), n = 2 1.0 0.79 0.96 1.2
 R1–2 (α4):53.2.1 (control), n = 2 1.0 0.89 1.2 1.1
 PS/2 (α4):53.7.3 (control), n = 2 1.0 0.50 0.82 1.0
Anti-CD44 mAb vs. control mAb
 IM7.8.1 (CD44):53.7.3 (control), n = 2 1.0 0.49 1.0 1.3
 IM7.8.1 (CD44):53.2.1 (control), n = 2 1.0 0.39 1.0 Not determined
Anti-CD44 mAb vs. antiintegrin α4 mAb
 R1–2 (α4):IM7.8.1 (CD44), n = 2 1.0 1.3 1.1 0.90
Control
 No Ab:No Ab 1.0 1.0 1.1 1.1
*

Each mouse received simultaneously two sets of 107 fluorescently labeled, antibody-treated T cells. The exact ratio of green and red cells in the initial cell mix was determined by fluorescence microscopy. Brain, spleen, and liver were harvested 5–24 h later and were snap-frozen. The results are given relative to the ratio of red vs. green T cells in various organs of sacrificed mice.