Table 1.
Growth inhibition of human cancer cells in vitro by doxorubicin and prodoxorubicin
| Time, hr | Treatment | IC50, μM
|
||
|---|---|---|---|---|
| HT29 | LIM1215 | LNCaP | ||
| 72 | doxorubicin | 3.0 | 0.4 | 0.4 |
| prodoxorubicin | >25 | 18 | 18 | |
| 120 | doxorubicin | 2.5 | 0.4 | 0.2 |
| prodoxorubicin | 22 | 10 | 8 | |
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