Table 1.
Immunocytochemical detection of p53 protein in epithelial tumor cells identified with various epithelial marker antigens in BM of cancer patients
| Epithelial marker | No. of BM samples, %
|
|||
|---|---|---|---|---|
| Total | Marker+ | p53+/marker+ | p53−/marker+ | |
| Total | 114 | 46 (40.3) | 4 (3.5) | 42 (36.8) |
| CK18 | 63 | 29 (46.0) | 4 (6.3) | 25 (39.7) |
| CK19 | 14 | 5 (35.7) | 0 | 5 (35.7) |
| Pan-CK | 17 | 8 (47.1) | 0 | 8 (47.1) |
| EGP-40/Lewis-Y | 20 | 4 (20.0) | 0 | 4 (20.0) |
Patients with carcinomas of the colon/rectum (n = 46), stomach (n = 27), stomach (n = 27), lung (n = 25), urogenital tract (n = 5), breast (n = 4), pancreas (n = 4), and cancer of unknown primary (n = 3).