Table 1.
Distribution of lesions and of S. suis serotype 2 as detected by culture and immunohistochemistry in 3 animals after aerosolic challenge.
| Tissue | Animals positive | Characteristic macroscopic and/or histologic lesions (Animals) | |
| Culture | IHC | ||
| Nasal cavity | C | A,C | Mild, focal mucopurulent rhinitis (A,C) |
| Lung | - | A | Diffuse fibrinopurulent pleuritis (A,B); acute embolic pneumonia (A) |
| Bronchial lnn. | - | A | Follicular hyperplasia and exudation of heterophils (A,B) |
| Middle ear | C | B | Unilateral purulent otitis media and exudate in Eustachian tube (B) |
| Inner ear | n.d. | C | Bilateral purulent labyrinthitis and perineuritis (n. vestibularis) (C) – Fig. 1 |
| Tonsil, pharyngeal | A,C | C | Focal exudation of heterophils (C) |
| Tonsil, soft palate | A,B,C | A,B,C | Heterophils in crypt epithelium and lumen (A,B,C) |
| Brain | C | C | Diffuse fibrinopurulent meningitis with focal submeningeal encephalitis (C) |
| Heart | A | A | Diffuse fibrinopurulent pericarditis (A) |
| Peritoneum | A | A | Diffuse fibrinopurulent peritonitis (A) |
| Mesenteric lnn. | - | A | Follicular hyperplasia and exudation of heterophils (A) |
| Liver | A | A | Multifocal, subcapsular hepatic necrosis and fibrinopurulent perihepatitis (A) |
| Spleen | C | A | - |
| Joints | A,C | A,C | Suppurative arthritis (A,C) |
| Blood | A | n.d. | - |
n.d.: not done; -: negative; IHC: immunohistochemistry for S. suis serotype 2; A,B,C: animal no.