Figure 3.

CpG-DNA has therapeutic potential for the treatment of leishmaniasis. The footpads of BALB/c mice were infected with parasite 4 h before injection with CpG-ODN 1826 (A), control ODN 1911 (B), or PBS (C) as described in Materials and Methods. Each line represents the progression of infection in an individual animal. ∗, Euthanized animals. These data are representative of four independent experiments.