Table 1.
Optimal sampling time and windows after administration of itraconazole capsules and solution for three groups with 10 patients per group
Capsule | Solution | |||
---|---|---|---|---|
Group | Optimal sampling time postdose (h.min) | Window (h.min) | Optimal sampling time postdose (h.min) | Window (h.min) |
1 | 1.14 | 0.06–3.00 | 0.17 | 0.06–1.00 |
8.56 | 7.00–10.00 | 3.55 | 3.00–3.30 | |
25.49 | 24.00–27.00 | 3.56 | 3.30–4.00 | |
51.45 | 50.00–53.00 | 3.56 | 4.00–4.30 | |
2 | 6.13 | 5.00–8.00 | 0.18 | 0.06–1.00 |
9.50 | 8.00–11.00 | 4.06 | 3.00–4.00 | |
29.29 | 28.00–29.30 | 4.06 | 4.00–5.00 | |
29.29 | 29.30–31.00 | 72.00 | 69.00–72.00 | |
3 | 8.08 | 7.00–10.00 | 0.17 | 0.06–1.00 |
28.00 | 26.30–29.30 | 4.22 | 3.00–6.00 | |
72.00 | 69.00–70.30 | 27.08 | 26.00–29.00 | |
72.00 | 70.30–72.00 | 72.00 | 69.00–72.00 |