Table 2.
Distribution of cases and controls and risk estimates of acute myocardial infarction by number of prescriptions of diclofenac
| No. of prescriptions | No. of cases | No. of controls | RR estimate* | 95% CI |
|---|---|---|---|---|
| 1 | 411 | 1866 | 1.0 | Ref. |
| 2–4 | 226 | 894 | 1.2 | 1.0, 1.4 |
| 5–9 | 81 | 251 | 1.4 | 1.1, 1.9 |
| 10–19 | 52 | 124 | 1.9 | 1.3, 2.7 |
| 20+ | 36 | 81 | 2.0 | 1.3, 3.0 |
| Total | 806 | 3216 |
*
Adjusted for body mass index, smoking, rheumatoid arthritis, hyperlipidaemia and use of other nonsteroidal anti-inflammatory drugs (≥10 prescriptions vs. <10, separately for ibuprofen, naproxen, and aspirin).