Table 3.
Distribution of cases and controls and risk estimates of acute myocardial infarction by number of prescriptions of ibuprofen
No. of prescriptions | No. of cases | No. of controls | RR estimate* | 95%CI |
---|---|---|---|---|
1 | 577 | 2425 | 1.0 | Ref. |
2–4 | 260 | 977 | 1.1 | 0.9, 1.3 |
5–9 | 51 | 175 | 1.2 | 0.9, 1.7 |
10–19 | 24 | 88 | 1.0 | 0.6, 1.6 |
20+ | 16 | 38 | 1.7 | 0.9, 3.1 |
Total | 928 | 3703 |
Adjusted for body mass index, smoking, rheumatoid arthritis, hyperlipidaemia and use of other nonsteroidal anti-inflammatory drugs (≥10 prescriptions vs. <10, separately for naproxen, diclofenac, and aspirin).