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. 2007 May 17;64(5):662–667. doi: 10.1111/j.1365-2125.2007.02942.x

Table 3.

Distribution of cases and controls and risk estimates of acute myocardial infarction by number of prescriptions of ibuprofen

No. of prescriptions No. of cases No. of controls RR estimate* 95%CI
1 577 2425 1.0 Ref.
2–4 260 977 1.1 0.9, 1.3
5–9 51 175 1.2 0.9, 1.7
10–19 24 88 1.0 0.6, 1.6
20+ 16 38 1.7 0.9, 3.1
Total 928 3703
*

Adjusted for body mass index, smoking, rheumatoid arthritis, hyperlipidaemia and use of other nonsteroidal anti-inflammatory drugs (≥10 prescriptions vs. <10, separately for naproxen, diclofenac, and aspirin).