Figure 1.

Structural-based multiple-sequence alignment of the zf-HIT domain, based on seed sequences from Pfam. (★) The seven Cys and one His residues for coordination with zinc atoms are numbered at the bottom of the sequence. Labels and elements of secondary structures are reported above the aligned sequences. The three subgroups are shown with different colors for the title of the sequence. (Red) The first subgroup; (green) second subgroup; (blue) third subgroup. The sequence alignment output was made with the ESPript program (Gouet et al. 1999).