Figure 7.

Superposition of the ZNHIT2 zf-HIT domain with the known domain structures of (A) the B-box (2FFW), (B) RING (1CHC), (C) PHD (2G6Q), (D) C₂H₂ (1UN6, finger5 of TFIIIA), and (F) cys2 domain of PKCδ (1PTQ). In each case, the zf-HIT domain is colored as in its ribbon diagram in Figure 3; the B-box, RING, PHD, C₂H₂ and cys2 domains are colored green, yellow, blue, orange, and purple, respectively. (E) Ribbon diagram of the cys2 domain of PKCδ. The side chains of the coordinating residues are shown in stick models (blue). Zinc ions are presented by yellow spheres.