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. Author manuscript; available in PMC: 2008 Apr 1.
Published in final edited form as: Am J Physiol Endocrinol Metab. 2006 Dec 5;292(4):E1000–E1009. doi: 10.1152/ajpendo.00493.2006

Figure 8.

Figure 8

Changes in LHRH release in the stalk-median eminence during pubertal development in sham/control animals. Group means (± SEM) are shown. The number of sham/control monkeys in each developmental period was 4–5. Approximate age of sham lesion (in 3 animals) and menarche are indicated by arrows. Note that the first elevated LHRH levels were observed at 25–29 months of age. LHRH levels further increased after 30 months of age. A significant increase in the evening and morning LHRH levels started to occur at 25–29 months, and 30–34 months of age, respectively, and the increase continued until the end of the examination. ***: p<0.001 vs. 15–17 months; **: p<0.01 vs. 15–17 months; *: p<0.05 vs. 15–17 months; ##: p<0.01 vs. 25–29 months; #: p<0.05 vs. 25–29 months; aa: p<0.01 vs. morning levels at each age; a: p<0.05 vs. morning levels at each age.