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. Author manuscript; available in PMC: 2008 Apr 1.
Published in final edited form as: Am J Physiol Endocrinol Metab. 2006 Dec 5;292(4):E1000–E1009. doi: 10.1152/ajpendo.00493.2006

Table 2.

Acute effects of posterior hypothalamic lesions on the inter-pulse intervals (IPI) and pulse amplitude of LHRH release

Groups AM IPI (min) PM IPI (min) AM Amplitude (pg/ml) PM Amplitude (pg/ml)

Lesions (N = 6)
 15–17 months 137.7±35.1# 114.7±11.5 1.4±0.2 1.3±0.2
 18–20 months 47.7±5.1**,a 51.2±1.6***,aa 3.4±1.0*,a 5.0±1.6*,a
 21–24 months 55.0±5.2***,a 50.2±2.6*** 5.1±1.3*,a 6.6±1.4**,a
 25–29 months 49.6±2.9*** 54.2±3.1*** 8.6±3.1* 10.6±3.2*
 30–3å4 months 56.4±2.1*** 54.3±3.6*** 7.4±2.6* 8.7±1.5**
 > 35 months 44.5±3.3*** 48.4±1.3*** 11.6±5.0* 14.2±5.0*

Sham/controls (N=5)
 15–17 months 135.7±16.8 99.2±15.6 1.3±0.3 1.2±0.1
 18–20 months 132.0±30.9 122.0±23.1 1.5±0.3 1.8±0.8
 21–24 months 115.2±19.4 73.2±9.1 2.0±0.3 1.8±0.8
 25–29 months 71.8±8.6** 58.0±3.6* 2.1±0.4 4.8±1.4*
 30–34 months 54.3±3.6*** 51.1±5.1** 9.3±3.5* 15.7±3.5**
 > 35 months 57.3±5.2*** 47.5±3.6** 7.4±2.6* 17.1±4.5**
#

Mean±SEM

*

p<0.05 vs. 15–17 months;

**

p<0.01 vs. 15–17 months;

***

p<0.001 vs. 15–17 months (within group)

a

p<0.05 vs. sham/controls at corresponding age;

aa

p<0.01 vs. sham/controls at corresponding age (between groups)