Table 4.
Mean percent volume of OAR receiving various dose levels for N2-3 and/or T4 patients (upper limit of fields at L5-S1) for a 59.4 Gy treatment
| Mean volume receiving above threshold dose (%)† | |||||
| Organ | Threshold dose (Gy) | A | B | C | D |
| Bladder | 30 | 100 | 88.6* (76–100) | 84.9* (71–99) | 77.0* (68–84) |
| 40 | 100 | 60.2* (43–74) | 52.5* (39–70) | 39.0* (30–54) | |
| Genitalia/perineum | 30 | 87.0 (60–100) | 64.4 (26–93) | 46.2* (26–68) | 32.8* (20–53) |
| 40 | 85.1 (56–99) | 25.9* (2–43) | 9.8* (1–26) | 7.4* (0–26) | |
| Small bowel | 30 | 64.4 (48–89) | 43.6* (38–52) | 43.0* (37–50) | 45.8 (39–55) |
| 40 | 62.1 (45–87) | 26.5* (21–30) | 25.8* (19–30) | 28.3* (20–35) | |
| Iliac crests | 10 | 59.9 (57–63) | 52.2* (45–57) | 51.4* (45–56) | 56.0 (47–60) |
| 20 | 50.2 (47–54) | 33.0* (30–37) | 32.8* (30–37) | 34.3* (30–38) | |
| Femoral heads | 45 | 29.9 (21–39) | 15.7* (8–21) | 8.8* (6–14) | 14.6* (11–17) |
†Mean in % (range).
* denotes statistically significant p values (p < 0.05) as compared with arm A.