Table 3.

Adverse events associated with FLV and FLV+TJ-43 treatment.

	FLV	FLV+TJ-43
Adverse events	Number (%) of patients reporting event
GI symptoms
Nausea	9 (36)	center3 (12)	*
Anorexia	3 (12)	3 (12)
Abdominal fullness	1 (4)	0 (0)
Constipation	1 (4)	0 (0)
Diarrhea	1 (4)	0 (0)
Feel discomfort	3 (12)	2 (8)
Feel irritable	1 (4)	0 (0)
Difficulty in urinating	1 (4)	0 (0)
General fatigue	1 (4)	0 (0)
Tremor	0 (0)	1 (4)
	/25	/25

FLV = fluvoxamine; TJ-43 = Rikkunshito; GI:gastrointestinal. * p < 0.05 by Fisher exact probability test.