Table 1.
Subject Characteristics with Radiographic Hip OA and Controls at Visit 5
| Characteristic | RHOA Cases | Controls | p value |
|---|---|---|---|
| Number | 569 | 4134 | -- |
| Age (yrs) | 79.6 ± 5.0 | 78.4 ± 4.6 | <0.01 |
| Height (cm) | 157.6 ± 6.3 | 157.7 ± 6.2 | 0.60 |
| Weight (kg) | 66.3 ± 12.8 | 66.2 ± 12.8 | 0.84 |
| BMI (kg/m2) | 26.7 ± 5.0 | 26.6 ± 4.8 | 0.48 |
| Age at Menopause (yrs) | 48.4 ± 5.4 | 48.2 ± 5.6 | 0.63 |
| Current Estrogen Use (%) | 17.4 | 19.1 | 0.34 |
| Current Vitamin D Use (%) | 48.2 | 47.9 | 0.91 |
| Smoking (%) | 4.4 | 4.8 | 0.64 |
| Health Status, Good/Excellent (%) | 73.6 | 81.3 | <0.01 |
| Areal BMD by DXA (g/cm2) | |||
| Total Hip | 0.74 ± 0.13 | 0.73 ± 0.14 | 0.53 |
| Femoral Neck | 0.67 ± 0.14 | 0.62 ± 0.11 | <0.01 |
| Genotype Frequencies | |||
| Pvu II | |||
| TT (%) | 188 (33.2) | 1162 (28.3) | 0.03 |
| TC (%) | 277 (48.9) | 2067 (50.3) | |
| CC (%) | 102 (18.0) | 884 (21.5) | |
| Xba I | |||
| AA (%) | 257 (45.2) | 1700 (41.2) | 0.20 |
| AG (%) | 250 (43.9) | 1932 (46.9) | |
| GG (%) | 62 (10.9) | 491 (11.9) |
Continuous values are noted in mean ± SD, dichotomous values noted as percentage. p values are from Chi-square test for dichotomous variables and from Student’s t-test for continuous variables.