The effects of repeated icv administration (once daily for three days) of POMC-derived peptide on body composition. (A) Total lean and fat mass assessed by DEXA (B) Total liver mass and regional fat depot mass, meso=mesenteric fat, retro= retroperitoneal fat, gonad= gonadal fat, subcut= subcutaneous, (n=6-8 per group, * p<0.05, **p<0.01 vs sham).