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SCC-25 morphology displayed differential responses to HPV. SCC-25 cells (A) were plated in 96-well plates and allowed to proliferation with 10% FBS for three days. (A) HPV16-transfected cells exhibited a profound increase in absolute number, confluence and cell spreading, while (B) HPV18- and (C) HPV16/18-transfected cells demonstrated visible decreases in cell number, spreading and confluence by day 3.
