Table 3.
Mean (SD) peak plasma concentration (Crmax, mM), time to peak concentration (Tmax, h), area under the plasma concentration curve (AUC, mM.h), velocity constant of absorption (ka, h-1) and velocity constant of elimination (ke, h-1) following ingestion of isomolar amounts of creatine (4.4 g) in the form of creatine monohydrate (CrM), tri-creatine citrate (CrC), or creatine pyruvate (CrPyr). Means differing significantly are denoted by the letters a to c.
| CrM (a) | CrC (b) | CrPyr (c) | ANOVA P value | ||||
| Mean | SD | Mean | SD | Mean | SD | ||
| Crmax | 751 | 32.9 | 837 c | 71.5 | 968 a | 82.3 | 0.008 |
| Tmax | 1.5 c | 0.13 | 1.2 | 0.1 | 1.1 a | 0.08 | 0.002 |
| AUC | 2384 | 376.5 | 2627 | 506.8 | 2985 | 540.6 | 0.023 |
| ka | 1.26 | 0.214 | 1.39 | 0.551 | 1.31 | 0.324 | NS |
| kel | 0.73 | 0.344 | 0.66 | 0.279 | 0.72 | 0.279 | NS |