Figure 5.—

Ty1 insertions in the CAN1 promoter region vs. the coding sequence. Shaded bars, Ty1 insertions in the CAN1 promoter region; solid bars, Ty1 insertions in the CAN1 coding sequence. On the bottom are Ty1 restriction genes that were analyzed. P-values were obtained by comparing the distribution of promoter vs. coding sequence insertions in WT and Ty1 restriction mutants (‡, refer to materials and methods). Also refer to supplemental data for more information on the spectrum of Can^R mutations (supplemental Tables S4 and S5), the orientation of the Ty1 insertions (supplemental Table S6), and DNA sequence analysis of Ty1 insertions when PAF1 was deleted (supplemental Figure S5).