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. 2008 Jan;178(1):197–214. doi: 10.1534/genetics.107.082602

TABLE 1.

Overrepresentation analysis of Ty1 restriction mutants

Gene ontology biological process (GOBP) List hits List total Population hits Population total P-value (×10−10)
Double-strand break repair 12 85 39 6455 0.000358
Nucleic acid metabolism 51 85 1490 6455 0.00223
Nonrecombinational repair 10 85 27 6455 0.00641
Response to DNA damage stimulus 19 85 194 6455 0.0374
Double-strand repair via homologous recombination 8 85 17 6455 0.143
Recombinational repair 8 85 17 6455 0.143
Chromosome organization and biogenesis (sensu Eukaryota) 20 85 237 6455 0.15
Negative regulation of DNA transposition 6 85 8 6455 1.2
Nuclear organization and biogenesis 20 85 297 6455 8.91
DNA recombination 16 85 187 6455 17.7
Transcription/DNA dependent 23 85 441 6455 58.2
Meiotic recombination 8 85 39 6455 286
Cell cycle 23 85 530 6455 1830
Establishment and maintenance of chromatin architecture 14 85 202 6455 2950
Telomerase-independent telomere maintenance 5 85 13 6455 4170
Cell proliferation 24 85 601 6455 4360
Chromatin modification 13 85 178 6455 4490

List hits, number of Ty1 restriction genes associated with the designated GOBP term; list total, number of Ty1 restriction genes associated with at least one GOBP term; population hits, the number of unique genes annotated for the designated GOBP term; population total, the number of unique genes annotated for a GOBP term; P-value, one-sided Fisher's exact test.