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. 2008 Jan;178(1):527–538. doi: 10.1534/genetics.107.081521

TABLE 3.

Detection and estimation for simulated QTL in case II

Effectd
Inferred modee
Simulated QTL Methoda Powerb Positionc 2a apat amat d E1 E2 E3 E4
QTL1 (LG1: 25 cM, E4) (amat = −0.25) Bayes 0.80 25.3 (4.1) −0.26 (0.04) 0.01 (0.04) 0.01 (0.11) 0.00 (0.00) 0.78 (0.85)
IM 0.57 28.4 (12.6) −0.21 (0.02) 0.01 0.21 0.15 0.20
QTL2 (LG1: 75 cM, E1) (2a = 0.5, d = 0.0) Bayes 0.99 75.4 (3.6) 0.47 (0.08) 0.03 (0.11) 0.95 (0.83) 0.02 (0.14) 0.02 (0.02) 0.00 (0.01)
IM 0.98 76.1 (3.9) 0.39 (0.07) 0.02 (0.14) 0.67 0.14 0.17 0.00
QTL3 (LG2: 65 cM, E3) (apat = 0.2) Bayes 0.71 61.9 (9.7) 0.21 (0.04) 0.07 (0.13) 0.03 (0.14) 0.61 (0.72) 0.00 (0.01)
IM 0.64 62.6 (12.5) 0.24 (0.03) 0.12 0.04 0.48 0.00

The proportions of MCMC iterations fitting QTL1 and QTL2 simultaneously in each analysis were averaged as 0.82 ± 0.27.

a

Bayes, Bayesian method; IM, interval mapping.

b

Proportion of replicates that successfully detected each QTL with genomewide significance level of P = 0.05 in a total of 100 replicates.

c

Average of estimated QTL positions calculated in the replicates with successful detection of QTL with standard deviations given in parentheses.

d

Average of estimated QTL effects corresponding to the simulated expression mode over the replicates with successful QTL detection with standard deviations given in parentheses.

e

Proportion of replicates supporting each QTL expression mode as the most probable state in the replicates with successful detection of QTL. Averages of posterior probabilities of QTL expression modes are given in parentheses for the Bayesian method. Prior probabilities of expression modes E1, E2, E3, and E4 were 0.6, 0.2, 0.1, and 0.1, respectively, and transition probabilities among expression modes were set at δ = 0.2, κ = 0.6, ω = 0.1, η = 0.1, and ζ = 0.1.