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. 2008 Jan;178(1):553–561. doi: 10.1534/genetics.107.080838

TABLE 4.

Estimated haplotype, polygenic, total genetic (±SE), and residual (±SE) variances and heritabilities at different values of r2 between adjacent markers for the high-heritability trait

Analysis r2 SNP Haplotype Polygenic Total geneticab Residuala h2
Simulatedc 0.50 0.50 0.50
Polygenic 0.485 0.455 0.516
SNP1 0.099 0.220 0.412 0.632 0.481 0.543
0.123 0.103 0.379 0.482 0.490 0.491
0.147 0.163 0.274 0.437 0.501 0.454
0.191 0.353 0.150 0.503 0.517 0.463
0.213 0.303 0.090 0.393 0.524 0.420
SNP2 0.099 0.155 0.361 0.516 0.489 0.502
0.123 0.111 0.328 0.439 0.499 0.464
0.147 0.193 0.216 0.409 0.507 0.436
0.191 0.347 0.100 0.447 0.521 0.440
0.213 0.315 0.046 0.361 0.514 0.398
HAP_IBD2 0.099 0.165 0.088 0.253 0.472 0.347
0.123 0.200 0.077 0.276 0.463 0.370
0.147 0.195 0.049 0.244 0.464 0.340
0.191 0.195 0.028 0.222 0.452 0.328
0.213 0.228 0.019 0.247 0.442 0.356
HAP_IBD10 0.099 0.178 0.100 0.278 0.471 0.370
0.123 0.214 0.086 0.299 0.468 0.387
0.147 0.223 0.045 0.268 0.476 0.357
0.191 0.233 0.037 0.269 0.472 0.362
0.213 0.262 0.028 0.290 0.462 0.383
a

Standard errors across replicates were calculated as the standard deviation of the estimated variances divided by Inline graphic and ranged from 0.013 to 0.102 for the total genetic variance and from 0.009 to 0.020 for the residual variance.

b

The sum of estimated QTL and polygenic variances.

c

The average simulated QTL and residual variances across replicates.