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. 2008 Jan;178(1):553–561. doi: 10.1534/genetics.107.080838

TABLE 5.

Estimated haplotype, polygenic, total genetic (±SE), and residual (±SE) variances and heritabilities at different values of r2 between adjacent markers for the low-heritability trait

Analysis r2 SNP Haplotype Polygenic Total geneticab Residuala h2
Simulatedc 0.10 0.90 0.10
Polygenic 0.143 0.873 0.140
SNP1 0.103 0.016 0.128 0.144 0.869 0.141
0.120 0.020 0.109 0.129 0.872 0.128
0.152 0.029 0.089 0.118 0.874 0.119
0.189 0.043 0.070 0.113 0.863 0.116
0.210 0.054 0.053 0.107 0.863 0.110
SNP2 0.103 0.021 0.125 0.146 0.867 0.143
0.120 0.027 0.108 0.134 0.868 0.133
0.152 0.037 0.080 0.117 0.871 0.119
0.189 0.053 0.058 0.111 0.864 0.113
0.210 0.065 0.048 0.113 0.859 0.117
HAP_IBD2 0.103 0.036 0.079 0.114 0.866 0.116
0.120 0.044 0.063 0.107 0.862 0.110
0.152 0.048 0.050 0.099 0.855 0.103
0.189 0.069 0.037 0.106 0.847 0.111
0.210 0.085 0.034 0.119 0.835 0.125
HAP_IBD10 0.103 0.031 0.094 0.125 0.865 0.126
0.120 0.042 0.077 0.119 0.861 0.121
0.152 0.051 0.055 0.106 0.865 0.110
0.189 0.068 0.045 0.112 0.855 0.116
0.210 0.084 0.045 0.129 0.847 0.132
a

Standard errors across replicates were calculated as the standard deviation of the estimated variances divided by Inline graphic and ranged from 0.003 to 0.010 for the total genetic variance and from 0.002 to 0.008 for the residual variance.

b

The sum of estimated QTL and polygenic variances.

c

The average simulated QTL and residual variances across replicates.