TABLE 5.

Summary of sequenced ura3 and can1 mutations

Mutation	URA3	CAN1
T → C	4	4
T → A	14	9
T → G	5	5
C → T	16	20
C → A	40	21
C → G	11	9
A → T	8	4
A → C	6	5
A → G	0	1
G → T	28	20
G → C	9	12
G → A	26	40
Transitions	46	65
Transversions	121	85
One-base-pair deletions	22	56
One-base-pair insertions	3	8
Complex	15	13