Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2007 Aug 14;9(4):R79. doi: 10.1186/ar2278

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2007 Sharma et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Immunohistochemistry to assess glycosaminoglycan distribution. Cartilage sections immunohistochemically stained for (a,b) chondroitin-4-sulphate and (c,d) chondroitin-6-sulphate. Repair tissue from autologous chondrocyte implantation (ACI)-treated patients with the highest (a) (22-year-old) and lowest (b) (52-year-old) levels of chondroitin-4-sulphate measured by fluorophore-assisted carbohydrate electrophoresis (FACE). Biopsies of cartilage from a 22 yr old ACI patient (c) and its age-matched control (d) immunostained for chondroitin 6-sulphate. The pattern of immunostaining in repair tissue from the ACI-treated patient (c) with the highest levels of chondroitin-6-sulphate as measured by FACE demonstrated a pericellular pattern, similar to that seen in the age-matched cadaveric control tissue but there was also more widespread matrix staining (d).