Figure 1.
Alignment of murine and human cholesterol 24-hydroxylase protein sequences. The cDNA-deduced sequences of the enzymes are shown in single-letter code with identical residues highlighted in black. Amino acids are numbered on the right. An asterisk above the alignment marks a cysteine residue (position 437) conserved in P450 enzymes. The GenBank accession numbers for the murine and human cDNAs are AF094479 and AF094480, respectively.