Table 1.

Drugs having 'membrane stabilising activity' with the potential for severe cardiotoxicity depending on dose

Anti-arrhythmics class I Vaughan Williams	Flecainide, disopyramide, cibenzoline, propafenone, quinidine, lidocaine, procainamide
Beta-blockers	Propranolol, acebutolol, nadoxolol, pindolol, penbutolol, labetalol, oxprenolol
Polycyclic antidepressants	Imipramine, desipramine, amitritptyline, clomipramine, dosulepin, doxepin, maprotiline
Selective serotonin reuptake inhibitors	Include venlafaxine, citalopram
Dopamine and norepinephrine uptake inhibitors	Include bupropion
Anti-epileptics	Include carbamazepine, phenytoin
Phenothiazines	Include thioridazine
Opioids	Include dextropropoxyphene
Antimalarial agents	Include chloroquine and quinine
Anaesthetic-recreational agents	Include cocaine