. 2007 Apr 30;11(2):R51. doi: 10.1186/cc5904

Table 3.

Time course of renal functional variables and alpha-1-microglobuline excretion

		t0	t2	t6	t10	t14
UV (milliliters per minute)	ADR	3.3 ± 1.3^b	2.7 ± 1.3	1.7 ± 0.7^a	1.6 ± 0.7^a	1.3 ± 0.5^a
	MIL	3.2 ± 1.9^b	3.5 ± 2.8	2.1 ± 0.8^a	1.5 ± 0.4^a	1.4 ± 0.6^a
	CON	5.6 ± 2.6	4.8 ± 2.3	2.5 ± 0.9^a	1.9 ± 0.6^a	1.6 ± 0.6^a

C_Crea(milliliters per minute)	ADR	82.1 ± 30.5	76.0 ± 16.5	111.7 ± 59.5	120.6 ± 61.5	121.2 ± 62.2
	MIL	132.1 ± 55.6	149.7 ± 87.8	119.2 ± 36.5	119.3 ± 40.4	116.4 ± 58.6
	CON	135 ± 62.5	134.7 ± 51.8	150.6 ± 53.9	152.7 ± 37.0	136.3 ± 51.0

FE_Na(percentage)	ADR	4.0 ± 2.2	2.8 ± 1.8	1.3 ± 1.3^a	1.6 ± 1.3^a	1.4 ± 0.7^a
	MIL	2.2 ± 1.1	2.4 ± 2.6	1.5 ± 1.1	0.9 ± 0.8^a	1.0 ± 0.7^a
	CON	2.9 ± 2.4	2.5 ± 1.9	1.5 ± 0.6^a	1.1 ± 0.5^a	1.3 ± 0.6^a

A1-MG_U(milligrams per mole of creatinine)	ADR	225 ± 118	292 ± 133^bc	200 ± 85^ab	154 ± 63^ab	135 ± 60^ab
	MIL	206 ± 73	186 ± 75	156 ± 67^a	117 ± 51^ab	105 ± 46^a
	CON	208 ± 64	170 ± 67^a	110 ± 48^a	71 ± 28	72 ± 50^a

The time course of renal function parameters (urine flow [UV], creatinine clearance [C_Crea], fractional excretion of sodium [FE_Na], and the urinary excretion of alpha-1-microglobuline [A1-MG_U]) in patients who presented with myocardial dysfunction (cardiac index of less than 2.2 liters/minute per square meter despite optimization of mean arterial pressure and filling pressures) upon intensive care unit admission and who were treated with adrenaline (ADR) or milrinone (MIL) and of control patients (CON) not needing inotropic after coronary artery bypass grafting with cardiopulmonary bypass. ^aSignificant difference (p < 0.05) in comparison with baseline (t0); ^bsignificant difference (p < 0.05) in comparison with the control group; ^csignificant difference (p < 0.05) between the adrenaline and the milrinone group.