Table 3.
A comparison between survivors and non-survivors
| Characteristic | Survivor group (n = 18) | Non-survivor group (n = 18) | P |
| Age, years | 54.5 ± 14.7 | 57.3 ± 15.2 | 0.580 |
| Sex | |||
| Male | 11 (61.1) | 14 (77.8) | 0.471 |
| Female | 7 (38.9) | 4 (22.2) | |
| BMI, kg/m2 | 22.9 ± 2.3 | 21.7 ± 3.1 | 0.283 |
| Smoking, pack-years | 21.8 ± 23.6 | 19.9 ± 20.7 | 0.873 |
| Duration of symptom, days | 21.7 ± 33.5 | 15.2 ± 13.1 | 0.888 |
| CCS | 1.9 ± 1.3 | 3.2 ± 2.1 | 0.030 |
| SAPS II score | 35.2 ± 9.3 | 37.6 ± 7.9 | 0.425 |
| APACHE II score | 16.9 ± 5.4 | 17.6 ± 4.9 | 0.700 |
| Time to OLB, days | 3.8 ± 2.0 | 6.8 ± 6.4 | 0.061 |
| OLB time, early/late | 17/1 | 10/8 | 0.018 |
| Immunocompromised status | 3 (17) | 7 (39) | 0.137 |
| OLB complication | 8 (44) | 12 (67) | 0.180 |
| Ventilation duration, days | 14.9 ± 15.5 | 19.9 ± 12.0 | 0.282 |
| Number of organ dysfunctions | |||
| On MICU admission | 1.5 ± 0.6 | 1.7 ± 0.7 | 0.308 |
| On day of OLB | 1.5 ± 0.6 | 2.0 ± 0.8 | 0.039 |
| SOFA score | |||
| On MICU admission | 5.3 ± 2.5 | 6.2 ± 2.3 | 0.249 |
| On day of OLB | 4.3 ± 2.1 | 6.7 ± 2.7 | 0.005 |
| Maximum | 6.1 ± 2.7 | 8.1 ± 2.9 | 0.042 |
| PaO2/FiO2ratio | |||
| On MICU admission | 131.3 ± 37.1 | 118.9 ± 55.9 | 0.439 |
| On day of OLB | 190.6 ± 67.6 | 135.4 ± 57.4 | 0.012 |
| PEEP, cmH2O | |||
| On MICU admission | 10.2 ± 3.1 | 11.3 ± 4.2 | 0.381 |
| On day of OLB | 9.4 ± 4.3 | 11.3 ± 2.4 | 0.112 |
| Compliance, ml/cmH2O | |||
| On MICU admission | 16.7 ± 7.7 | 15.8 ± 5.5 | 0.703 |
| On day of OLB | 17.1 ± 8.4 | 15.5 ± 7.5 | 0.550 |
Data are presented as mean ± SD or n (%). BMI, body mass index; CCS, Charlson age–comorbidity score; SAPS, Simplified Acute Physiology Score; APACHE II, Acute Physiologic and Chronic Health Evaluation II; OLB, open lung biopsy; early OLB, OLB within 1 week of mechanical ventilation; MICU, medical intensive care unit; SOFA, Sequential Organ Failure Assessment; PEEP, positive end-expiratory pressure.