Table 2.

Results of the inflammatory mediators and cardiac troponin I

	t1	t2	t3	t4	t5	t6	p
C-reactive protein (mg/l)
Group A	3.7 (1.0–22.6)				79.9 (50.0–131.7)	112.0 (61.1–177.6)	<0.001†
Group B	2.6 (0.6–10.5)				87.6 (52.4–143.0)	131.0 (71.0–228.0)	<0.001†
	p = 0.068*				p = 0.092*	p = 0.168*
IL-6 (pg/ml)
Group A	1.6 (0.4–21.8)		95.0 (13.6–405.1)	46.3 (16.1–149.5)			<0.001†
Group B	2.0 (0.4–60.6)		130.5 (21.7–353.8)	49.2 (14.8–214.5)			<0.001†
	p = 0.107*		p = 0.829*	p = 0.482*
IL-6r (ng/ml)
Group A	43.6 (1.7–125.0)		47.4 (0.7–109.5)	56.2 (25.2–226.3)			0.949†
Group B	40.7 (15.6–94.6)		42.4 (22.2–100.5)	50.2 (13.2–104.9)			0.861†
	p = 0.607*		p = 0.914*	p = 0.304*
IL-10 (pg/ml)
Group A	1.9 (0.2–24.0)	47.2 (2.3–476.6)	7.2 (1.3–90.9)				<0.001†
Group B	2.6 (0.8–9.7)	209.7 (16.3–814.3)	56.1 (3.6–225.1)				<0.001†
	p = 0.136*	p = 0.001*	p = 0.001*
Soluble endothelial leukocyte adhesion molecule-1 (ng/ml)
Group A	88.6 (49.8–194.5)			88.5 (14.4–189.6)	72.7 (8.9–163.1)		0.058†
Group B	49.0 (18.3–144.1)			130.7 (33.0–360.7)	72.6 (16.7–224.7)		<0.001†
	p < 0.001*			p = 0.033*	p = 0.957*
Cardiac troponin-I (ng/ml)
Group A	0.02 (0.01–0.022)				0.22 (0.07–0.85)	0.13 (0.03–0.75)	<0.001†
Group B	0.01 (0.01–0.016)				0.66 (0.10–1.28)	0.19 (0.03–0.80)	<0.001†
	p = 0.520*				p = 0.018*	p = 0.097*

Data presented as the median (range). t1, before anaesthesia; t2, 10 minutes after cardiac surgery on cardiopulmonary bypass (CPB); t3, 2 hours after CPB; t4, 4 hours after CPB; t5, 24 hours after CPB; t6, 44 hours after CPB. ^†Intraindividual differences (Friedman test), *between-group differences (Kruskal–Wallis test).