Table 1.
Commonly used medications that can produce hypoglycaemia and hyperglycaemia as adverse effects
| Adverse effect | Drugs |
| Hypoglycaemia | Angiotensin-converting enzyme inhibitors |
| Budesonide | |
| Chlorpromazine | |
| Disopyramide (isolated cases) | |
| Ethanol | |
| Quinine | |
| Hyperglycaemia | Adrenaline (ephinephrine) |
| β2 agonists (in diabetes) | |
| Ciclosporin | |
| Clonidine | |
| Corticosteroids | |
| Diazoxide | |
| Diuretics (mainly thiazides) | |
| Glucose | |
| Isoniazid | |
| Nicotinic acid | |
| Noradrenaline (norephinephrine) | |
| Octreotide | |
| Olanzapine | |
| Oral contraceptives | |
| Phenytoin | |
| Risperidone | |
| Rituximab | |
| Theophylline | |
| Miscellaneous | Acetazolamide (potentiates action of hypoglycaemics) |
| Amitriptyline (elevates or decreases blood sugar levels) | |
| Imipramine (isolated cases of increase or decrease in blood sugar levels) | |
| Pentamidine (life threatening hypoglycaemia, less severe hyperglycaemia) | |
| Tacrolimus (elevates or decreases blood sugar levels) | |
| Triamterene (impaired glucose metabolism [<1/100] [33]) |