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. Author manuscript; available in PMC: 2008 Dec 11.
Published in final edited form as: FEBS Lett. 2007 Nov 20;581(29):5611–5616. doi: 10.1016/j.febslet.2007.11.010

Fig. 4. Dicer has lower affinity for ssRNAs having a 3’-biotin.

Fig. 4

(A) Representative figure showing Dicer-ssRNA binding with ssRNA having a 3’-OH (lane 2) and ssRNA having a 3’-biotin (lane 4). (B) Dependence on Dicer concentration of Dicer binding to ssRNA having a 3’-biotin or a 3’-OH. Percentage of bound RNA was calculated by normalizing intensity of ssRNA-Dicer complexes to their respective unbound RNA at each concentration of Dicer.