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LCMV infection causes lethal hemorrhagic anemia in platelet-depleted mice. (A) Hct values (mean ± SD) of B10D2 mice (20 per group) injected with α-PLT (red line) or α-Irr (blue line) before infection with LCMV Arm or injected with α-PLT followed by NaCl instead of LCMV (gray line). (B) Kaplan–Meier survival curves of mice described in A and identified by lines of the same colors. (C–E) Skin photographs of representative mice described in A and killed 6 days after injection.
