Fig. 4.

Proliferative response to P. falciparum and SK antigens by total and CD25-depleted Fulani- and Mossi-derived PBMC. Unfractionated PBMC (white bars) and CD25-depleted PBMC (black bars) obtained from the 13 Mossi and the 13 Fulani included in the study were stimulated with P. falciparum extracts or SK antigens as control. Cell proliferation was evaluated by thymidine incorporation after a 5-day culture. (A) Data are presented as mean stimulation index (cpm of stimulated cultures/cpm of unstimulated cultures) ± SE of Mossi and Fulani. (B) Results are expressed as stimulation index of PBMC before (□) and after (■) CD25⁺ cell depletion for each individual donor.