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MyD88 does not control MCA-induced sarcomas that emerge from MyD88-deficient mice. Groups of five WT (filled symbols) and MyD88−/− (open symbols) mice were challenged s.c. with increasing tumor cell numbers (circles, 104; triangles, 105; squares, 106) of M88–1 sarcoma (A) or M88–2 sarcoma (B), both derived from MyD88−/− mice. Mice were subsequently monitored for tumor growth, and data are presented as the mean tumor area ± SEM (n = 5 mice per group).
