Table 5.

Median values and median percentage change from baseline for serum lipid profiles (mITT population)

Lipid	Exemestane (n = 20)	Letrozole (n = 20)	Anastrozole (n = 19)	Placebo (n = 20)
LDL-C (mmol/L)
Baseline	4.2	4.2	4.2	3.8
Week 12, % change	-11	-4.5	-12	-6.1
Week 24, % change	-2.6	-4.2	-3.0	2.4
Week 36, % change	1.9	0.25	-5.7	-5.8
HDL-C (mmol/L)
Baseline, median	1.4	1.5	1.4	1.4
Week 12, % change	-4.4	9.0	1.7	-3.5
Week 24, % change	-13	-2.4	-4.4	-6.3
Week 36, % change	-6.9	-2.4	-2.5	-6.8
Total cholesterol (mmol/L)
Baseline, median	6.1	6.1	6.3	5.9
Week 12, % change	-6.8	-1.8	-3.7	-2.6
Week 24, % change	0.78	1.2	-0.68	0.75
Week 36, % change	1.3	-1.9	-5.8	-6.4
Triglycerides (mmol/L)
Baseline, median	1.1	1.2	1.2	1.0
Week 12, % change	-21	6.6	-10	-1.6
Week 24, % change	1.7	4.6	6.3	-7.0
Week 36, % change	-1.1	-5.4	-3.5	-0.28

HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; mITT = modified intent to treat.