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KChIP2d binding to Kv4.2 N-terminal peptide. (A) Surface plasmon resonance response curve of binding of KChIP2d (0.6875–44 μM) to immobilized Kv4.2NT in 1 mM CaCl2. (B) Binding curves in the absence (open boxes) and presence (closed boxes) of 1 mM CaCl2. Shown are fits to two-site models for interactions (see text).
