Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Gene targeting at the mRad50 locus
| Cell line (genotype) | Targeting vector | No. of colonies analyzed | No. targeted to wt allele* | No. targeted to mutant allele* |
|---|---|---|---|---|
| AB2 (+/+) | pTV2 | 159 | 20 (6.3%) | NA |
| AB2 (+/+) | pTV1 | 86 | 8 (4.7%) | NA |
| M2-1 (+/m2) | pTV1 | 146 | 0 | 6 (4.1%) |
| M2-2 (+/+/m2) | pTV1 | 92 | 7 (3.8%) | 7 (7.6%) |
NA, not applicable. wt, wild type.
Targeting frequency per locus in parentheses.
