Table 1.
Mutations in unc-64 and unc-31 cause constitutive dauer formation and increase life span
| Genotype | Percent of dauers at 26.8 ± 0.2°C* | Days lived at 20°C† |
|---|---|---|
| N2 (wild-type) | 12 ± 10 | 22 ± 5 (42) |
| unc-64(e246) | 99 ± 2 | 39 ± 12 (46) |
| unc-31(e928) | 93 ± 11 | 29 ± 12 (72) |
| daf-16(m27) | 6 ± 5§ | 18 ± 3 (47) |
| daf-16(m27); unc-64(e246) | 5 ± 4§ | 20 ± 5 (47) |
| daf-16(m27); unc-31(e928) | 8 ± 6§ | 19 ± 5 (104) |
| daf-5(e1385); unc-64(e246) | 99 | |
| daf-5(e1385); unc-31(e928) | 100 | |
| +/unc-64(e246)‡ | 9 | 23 ± 5 (14) |
| unc-64(e246)/unc-64(e246)‡ | 100 | 44 ± 14 (9) |
| unc-64(md1259)/unc-64(e246)‡ | 94 | 38 ± 8 (17) |
| unc-31(u280) | 100 | 29 ± 10 (40) |
The top part of the table gives the mean ± SD of five independent experiments at temperatures ranging between 26.6 and 27.0°C. Each experiment had at least 100 animals of each strain. The middle two lines give the mean of two experiments at 26.6 and 27.0°C. The bottom part of the table gives the results from a single experiment at 26.8°C.
The top part of the table combines the data from two independent experiments and gives the mean ± SD for the entire data set. No strain differed significantly from one experiment to the other (all P values > 0.15). The bottom part of the table gives the results from a single experiment. The number in parentheses is the number assayed.
This unc-64(e246) chromosome also carries dpy-18(e364).
Partial dauers (21).