Table 2.
Characterization of intron 4 regions of high flexibility
| Peak | Distance from exon 5, kb | Hybrid breaks | Distance from peak, kb | L1 and LTR (size in kb) | Distance from peak, kb |
|---|---|---|---|---|---|
| A | 55.4 | Aphidicolin-induced | 0.35 | L1 (0.3)/t | 2.5 |
| distal hybrid breaks/t | |||||
| B | 58.7 | cl3 hybrid break/c | 21 | ||
| C | 126.3 | Within L1 (0.7) | |||
| L1 (1.7)/t | 0.4 | ||||
| L1 (1.4)/c | |||||
| D | 140.8 | Within L1 (0.5) | |||
| L1 (0.4)/t | 0.1 | ||||
| L1 (1.5)/t | 2.4 | ||||
| E | 228 | LTR (0.5)/t | 6.1 | ||
| LTR (0.4)/t | 1.5 | ||||
| LTR (0.5)/c | 4.3 | ||||
| F | 235.6 | LTR (0.6)/t | 2.6 | ||
| LTR (0.5)/c | 0.6 | ||||
| G | 251.7 | Aphidicolin-induced | 7.1–7.6 | LTR (0.2)/t | 4 |
| proximal hybridbreaks/c | LTR (0.1)/t | 3.5 |
Positions of landmark hybrid breaks, cancer breaks, and repetitive sequences (LINE1 and LTR) near the seven flexibility peaks are listed. Sequences of peaks C and G showed 90% homology with each other over 40 bp. Aphidicolin-induced distal and proximal hybrid breaks (underlined) are close to peak A (0.35 kb) and not far from peak G (7.1–7.6 kb), respectively. /t, telomeric; /c, centromeric of indicated flexible peak.