Mean response rates (Responses/minute) in the terminal links and obtained delays (s) from the initial link to the terminal link when the terminal links were either FI 4 s and FI 8 s or FI 8 s and FI 16 s from each condition. Ranges are in parentheses. Dashes indicate instances in which there were no obtained-delay data because responding was completely suppressed.
| Subject Condition | Terminal-link rates |
Mean obtained delays |
||||||
| 4 | 8 | 16 | 8 | 4 | 8 | 16 | 8 | |
| 105 | ||||||||
| Control | 154.55 (128.39–175.97) | 73.39 (62.04–97.46) | 60.96 (43.27–73.41) | 74.03 (20.01–110.50) | 4.14 (4.11–4.18) | 8.17 (8.13–8.26) | 16.25 (16.17–16.49) | 8.32 (8.14–9.11) |
| Saline | 155.65 (141.43–169.86) | 72.57 (63.54–81.60) | 65.95 (59.51–72.40) | 73.78 (62.70–84.86) | 4.16 (4.16–4.17) | 8.20 (8.19–8.21) | 16.20 (16.16–16.23) | 8.20 (8.17–8.24) |
| 0.3 mg/kg | 148.07 (145.17–150.97) | 65.56 (65.38–65.73) | 74.66 (74.41–74.92) | 67.12 (59.57–74.78) | 4.13 (4.11–4.14) | 8.25 (8.19–8.31) | 16.20 (16.15–16.24) | 8.21 (8.18–8.24) |
| 1.0 mg/kg | 136.72 (112.04–161.39) | 65.68 (33.33–98.03) | 56.84 (54.64–59.03) | 51.39 (39.53–63.25) | 4.15 (4.11–4.18) | 8.28 (8.11–8.45) | 16.27 (16.15–16.38) | 8.24 (8.18–8.30) |
| 1.7 mg/kg | 115.55 (103.17–127.93) | 40.50 (40.04–40.96) | 61.51 (46.14–76.89) | 40.20 (25.18–55.22) | 4.17 (4.13–4.20) | 8.21 (8.20–8.22) | 16.50 (16.30–16.70) | 8.26 (8.18–8.34) |
| 3.0 mg/kg | 8.37 | 32.08 | 15.31 | 2.79 | 4.19 | 8.59 | 154.26 | 56.97 |
| 106 | ||||||||
| Control | 172.42 (159.77–184.96) | 68.04 (55.42–91.84) | 78.51 (67.97–93.13) | 68.46 (51.72–89.81) | 4.11 (4.09–4.14) | 8.17 (8.11–8.23) | 16.178 (16.14–16.29) | 8.16 (8.11–8.25) |
| Saline | 159.62 (158.19–161.04) | 75.56 (74.23–76.89) | 66.28 | 66.55 | 4.14 (4.13–4.15) | 8.29 (8.15–8.42) | 16.22 | 8.34 |
| 0.3 mg/kg | 172.14 (167.88–176.4) | 60.59 (51.76–69.43) | 77.81 (59.00–96.61) | 73.22 (70.23–76.20) | 4.11 (4.11) | 8.28 (8.21–8.34) | 16.2 (16.13–16.27) | 8.16 (8.14–8.18) |
| 1.0 mg/kg | 166.26 (153.59–178.92) | 62.09 (40.75–83.44) | 68.33 (31.00–140.59) | 64.22 (36.59–110.5) | 4.08 (4.08) | 8.14 (8.09–8.18) | 16.33 (16.17–16.42) | 8.23 (8.16–8.29) |
| 1.7 mg/kg | 156.86 (122.14–191.58) | 43.06 (20.11–66.01) | 75.68 (41.00–128.28) | 47.30 (35.71–62.04) | 4.08 (4.08) | 8.38 (8.13–8.62) | 16.35 (16.15–16.48) | 8.37 (8.14–8.57) |
| 3.0 mg/kg | 131.15 | 28.31 | 0 | 0 | 4.13 | 9.36 | — | — |
| 107 | ||||||||
| Control | 316.91 (288.40–364.94) | 108.46 (94.06–138.92) | 85.47 (62.25–109.98) | 120.59 (99.29–152.28) | 4.07 (4.06–4.09) | 8.08 (8.05–8.11) | 16.16 (16.10–16.26) | 8.08 (8.05–8.14) |
| Saline | 306.64 (258.76–354.52) | 96.85 (82.32–111.39) | 80.74 | 168.30 | 4.09 (4.09) | 8.14 (8.08–8.20) | 16.18 | 8.07 |
| 0.3 mg/kg | 356.56 | 96.30 | 89.67 (79.69–110.66) | 96.76 (79.53–120.91) | 4.09 | 8.10 | 16.52 (16.13–17.21) | 8.09 (8.05–8.11) |
| 1.0 mg/kg | 301.08 (298.03–304.14) | 110.3 (96.42–124.17) | 89.89 (72.75–107.03) | 117.22 (112.69–121.76) | 4.09 (4.06–4.11) | 8.09 (8.08–8.09) | 16.27 (16.22–16.32) | 8.09 (8.09) |
| 1.7 mg/kg | 225.82 (206.50–245.15) | 79.66 (78.76–80.57) | 73.58 (61.82–85.34) | 132.49 (94.68–170.29) | 4.13 (4.12–4.14) | 8.16 (8.13–8.19) | 16.36 (16.21–16.50) | 8.22 (8.15–8.28) |
| 3.0 mg/kg | 256.63 | 59.71 | 4.15 | 8.43 | ||||
| 108 | ||||||||
| Control | 90.26 (74.98–105.92) | 62.72 (53.31–70.72) | 52.02 (40.00–69.05) | 68.21 (49.14–93.69) | 4.35 (4.27–4.49) | 8.50 (8.29–8.74) | 16.35 (16.22–16.54) | 8.47 (8.29–8.74) |
| Saline | 90.97 (86.53–95.4) | 58.31 (44.42–72.20) | 51.45 (49.01–55.32) | 73.68 (67.00–64–83.03) | 4.39 (4.35–4.43) | 8.4 (8.31–8.48) | 16.3 (16.24–16.39) | 8.44 (8.35–8.60) |
| 0.3 mg/kg | 65.15 | 39.14 | 57.97 | 68.50 | 4.40 | 8.56 | 16.33 | 8.71 |
| 1.0 mg/kg | 83.07 (69.28–96.86) | 46.93 (39.50–54.35) | 61.1 (55.79–66.42) | 51.72 (50.92–52.52) | 4.29 (4.25–4.33) | 8.48 (8.31–8.65) | 16.37 (16.21–16.52) | 8.40 (8.38–8.41) |
| 1.7 mg/kg | 72.46 (69.80–75.12) | 35.84 (34.00–37.68) | 57.30 (50.50–64.18) | 52.37 (34.84–81.54) | 4.26 (4.25–4.26) | 8.55 (8.43–8.67) | 16.32 (16.24–16.36) | 8.41 (8.38–8.43) |
| 3.0 mg/kg | 46.51 (12.40–80.61) | 15.59 (12.16–19.01) | 65.54 | 41.57 | 5.90 (4.30–7.52) | 10.65 (9.38–11.92) | 16.25 | 8.42 |
| 225 | ||||||||
| Control | 62.71 (27.05–120.74) | 35.57 (17.74–66.10) | 39.18 (33.50–41.24) | 50.24 (41.68–56.68) | 4.8 (4.21–5.73) | 8.88 (8.30–9.58) | 16.25 (16.17–16.49) | 8.32 (8.14–9.11) |
| Saline | 67.85 (35.76–104.73) | 38.45 (11.26–52.39) | 33.46 (28.93–37.89) | 61.95 (46.28–75.62) | 4.90 (4.44–5.36) | 9.05 (8.24–10.07) | 16.62 (16.23–16.89) | 8.46 (8.19–8.75) |
| 0.3 mg/kg | 60.96 (47.29–74.63) | 35.62 (32.85–38.39) | 45.23 | 51.09 | 4.90 (4.69–5.11) | 9.00 (8.98–9.03) | 16.43 | 8.51 |
| 1.0 mg/kg | 90.09 (47.02–112.94) | 34.51 (29.19–43.34) | 26.52 (23.31–29.73) | 39.91 (30.10–49.73) | 4.27* (4.25–4.36) | 8.72* (8.62–9.08) | 18.25* (17.63–18.86) | 8.40* (8.30–8.49) |
| 1.7 mg/kg | 62.80 (26.96–98.65) | 20.53 (12.72–28.34) | 21.58 (14.13–28.67) | 19.58 (6.74–30.25) | 4.29* (4.19–4.39) | 9.96* (9.82–10.09) | 18.06* (17.09–19.20) | 9.47* (8.81–10.62) |
| 3.0 mg/kg | 55.31 | 18.11 | 44.70 | 9.34 | 4.52* | 9.42* | 18.69* | 9.64* |
| 226 | ||||||||
| Control | 117.62 (83.30–133.41) | 101.75 (82.57–122.70) | 84.54 (77.44–98.02) | 111.46 (101.51–115.89) | 4.40* (4.16–4.69) | 8.31* (8.11–8.72) | 16.24 (16.15–16.31) | 8.15 (8.09–8.29) |
| Saline | 124.72 (121.11–128.33) | 110.54 (106.08–115.01) | 82.29 (78.72–85.86) | 106.06 (98.46–113.66) | 4.26 (4.13–4.39) | 8.15 (8.13–8.17) | 16.26* (16.07–16.45) | 8.13* (8.13–8.14) |
| 0.3 mg/kg | 111.88 (95.39–128.38) | 109.71 (107.04–112.38) | 82.58 | 98.91 | 4.58 (4.31–4.84) | 8.27 (8.19–8.35) | 16.23* | 8.13* |
| 1.0 mg/kg | 122.08 (119.15–127.73) | 110.99 (99.10–117.60) | 79.34 (72.92–85.75) | 101.91 (100.83–102.99) | 4.38 (4.16–4.70) | 8.18 (8.13–8.22) | 16.28 (16.22–16.34) | 8.24 (8.12–8.37) |
| 1.7 mg/kg | 99.29 (69.59–128.98) | 63.99 (23.01–104.96) | 89.90 (67.84–110.11) | 109.95 (106.08–114.10) | 4.48 (4.29–4.67) | 8.85 (8.13–9.56) | 16.52* (16.15–17.19) | 8.19* (8.14–8.23) |
| 3.0 mg/kg | 127.90 | 90.04 | 99.15 | 114.72 | 4.17 | 8.20 | 16.46 | 8.21 |
| 227 | ||||||||
| Control | 122.59 (97.88–156.60) | 87.49 (64.30–108.24) | 79.93 (64.35–92.12) | 103.00 (90.59–111.59) | 4.23 (4.14–4.31) | 8.56 (8.13–10.42) | 16.27 (16.21–16.37) | 8.13 (8.08–8.18) |
| Saline | 99.25 (96.24–102.26) | 103.22 (99.35–107.08) | 75.68 (71.84–79.52) | 107.16 (99.14–115.18) | 4.27 (4.26–4.27) | 8.16 (8.14–8.17) | 16.32 (16.24–16.39) | 8.18 (8.17–8.19) |
| 0.3 mg/kg | 99.54 (95.35–103.74) | 73.33 (69.02–77.64) | 72.47 | 109.47 | 4.37 (4.37) | 8.15 (8.09–8.20) | 16.26 | 8.13 |
| 1.0 mg/kg | 127.39 (118.54–119.50) | 70.73 (62.12–71.63) | 54.30 (53.69–54.91) | 65.20 (60.77–69.63) | 4.17 (4.14–4.19) | 8.19 (8.18–8.21) | 16.38 (16.36–16.39) | 8.32 (8.31–8.33) |
| 1.7 mg/kg | 113.14 (106.10–120.19) | 41.00 (19.33–62.68) | 58.18 (29.30–84.84) | 59.48 (43.50–78.13) | 4.19 (4.16–4.21) | 11.30 (8.19–14.40) | 16.82 (16.36–17.52) | 8.33 (8.17–8.43) |
| 3.0 mg/kg | 7.10 | 0.12 | 5.50 | 4.98 | 5.29* | 149.72* | 22.15* | 11.36* |
| 228 | ||||||||
| Control | 116.93 (83.14–132.94) | 143.08 (99.51–178.15) | 66.96 (54.26–79.70) | 149.30 (123.62–181.05) | 4.21 (4.12–4.33) | 8.13 (8.10–8.22) | 16.33 (16.27–16.38) | 8.12 (8.10–8.17) |
| Saline | 133.02 (131.98–134.06) | 181.77 (181.03–182.51) | 79.90 (77.84–81.95) | 163.65 (147.10–180.20) | 4.16 (4.14–4.18) | 8.11 (8.10–8.12) | 16.35 (16.31–16.38) | 8.11 (8.09–8.13) |
| 0.3 mg/kg | 113.78 (98.20–129.37) | 136.25 (108.92–163.58) | 91.21 | 166.46 | 4.23 (4.20–4.26) | 8.11 (8.10–8.11) | 16.30 | 8.09 |
| 1.0 mg/kg | 127.20 (118.07–132.21) | 124.04 (102.50–166.67) | 61.13 (53.07–69.18) | 131.15 (120.91–141.38) | 4.15 (4.15–4.16) | 8.12 (8.11–8.13) | 16.34* (16.28–16.40) | 8.12* (8.12) |
| 1.7 mg/kg | 94.56 (90.80–98.33) | 15.98 (15.62–16.34) | 29.98 (0.00–89.92) | 50.75 (0.00–152.26) | 4.22* (4.15–4.29) | 16.94* (10.83–23.10) | 16.31 (16.31) | 8.10 (8.10) |
| 3.0 mg/kg | 9.78 | 2.61 | 0.00 | 0.00 | 4.49* | 35.01* | — | — |
* Due to a programming error, in a few of the sessions in which response rates were substantially suppressed (and obtained delays were substantially lengthened), it could not be determined conclusively to which alternative 1–2 of the obtained delays belonged. Therefore, under these conditions, we made our best guess regarding the assignment of these delays to a given alternative.