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. 2008 Jan 25;4(1):e19. doi: 10.1371/journal.pcbi.0040019

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© 2008 Liu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A–B) The time-dependence of the radii of L- and V-rings as the receptor rotates in clockwise and anticlockwise directions, respectively.

(C) Pore radius profiles versus position along the pore axis. Curves represent the radius changes at different time intervals for the all-atoms as the receptor rotates in clockwise direction.

(D) Bending vibrations of the M2 helices represented by changes of inclination angle along the SRMD trajectory of nAChR rotating in clockwise direction. The inclination angle has been defined in Figure 2A.