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. Author manuscript; available in PMC: 2008 Jan 22.
Published in final edited form as: Brain Res. 2007 Sep 14;1183:10–20. doi: 10.1016/j.brainres.2007.09.001

Figure 3. Effect of pH and Cysteine on proline transport.

Figure 3

Proline transport into 40 μg of crude synaptosomal fraction (P3 pellet) was measured in the presence of 10 mM MeAIB or 10 mM L-cysteine. (A) At pH 7.5 cysteine resistant transport activity of synaptosomes from v7−3 KO was significantly lower than the activity of wild type synaptosomes. (B) At pH 6.5 there was no difference in cysteine resistant transport activity between wild type and KO synaptosomes. At pH 6.5, cysteine resistant transport activity is significantly lower in the wild type synaptosomes (C), but not in the KO synaptosomes(D). Data are expressed as means ± SEM obtained from 3 independent experiments using triplicate samples.